Max Methyl contains all the cofactors and methyl donors needed to promote methylation: vitamin B6, vitamin B12, folate and trimethylglycine (TMG). Methylation is a key process essential to cell function, detoxification, and gene expression. Certain people, including those with an MTHFR genetic mutation, have trouble making active folate from regular folic acid, so Max Methyl includes L-5-MTHF (the active form), ensuring those individuals benefit as well. Ultimately, Max Methyl helps maintain normal homocysteine levels and supports cardiovascular and neurological health.