Promotes healthy estrogen metabolism Indole-3-carbinol I-3-C is a phytonutrient found in Brassica vegetables such as broccoli, kale and cabbage, and is one of the key health-promoting compounds in these foods. Many studies have had phenomenal success using I-3-C to shift the balance of metabolic enzymes that process estrogens thereby reducing the formation of bad estrogens and increasing the formation of good estrogens. Human studies in women taking I-3-C have shown a favourable shift in estrogen metabolism, and I-3-C has been shown to be protective against estrogen dominance. Estrogen dominance has been linked to fibroids, breast tenderness, premenstrual syndrome, endometriosis and other women’s health concerns.