PQQ plus CoQ10 Oxidative stress and mitochondrial damage have been implicated in age-related cognitive decline and many chronic diseases. Cogni-Q contains a high dose of the well-known antioxidant Coenzyme Q10 along with Pyrroloquinoline Quinone PQQ, a recently discovered B-vitamin-like nutrient. PQQ and CoQ10 have been studied in combination and were shown to improve memory and cognition in elderly subjects after just 3 months. They have also been shown to reduce neurodegeneration thanks to their antioxidant functions, their ability to reduce mitochondrial damage, and their involvement in cellular energy production. PQQ has shown the unique ability to signal and activate the generation of new mitochondria, an action that no other nutrient can do.